Ledoux pronunciation

Biography and Contact Details

 

 

Joseph LeDoux is a Professor of Neural Science at New York University, where he also directs the Emotional Brain Institute. His work is focused on the brain mechanisms of emotion, memory, and consciousness. LeDoux has received awards for his research (Karl Spencer Lashley Award from the American Philosophical Society; Fyssen International Prize in Cognitive Science; Jean Louis Signoret Prize from the IPSEN Foundation; Santiago Grisolia Prize; American Psychological Association Distinguished Scientific Contributions Award; American Psychological Association Donald O. Hebb Award; Jean-Marie Delwart Foundation 2016 International Prize for Molecular and Cellular Mechanisms Underlying Mood). LeDoux is anelected member of the National Academy of Sciences and the American Academy of Arts and Sciences and is the author of several books, including The Emotional Brain, Synaptic Self, Anxious, The Deep History of Ourselves, and The Four Realms ofExistence. He is also the subject of a documentary--Neuroscience and Emotions: The Li

My lab's research is aimed at understanding how the brain learns and stores information about danger. Using Pavlovian threat (fear) conditioning in rats, we have mapped pathways through which sensory stimuli enter and flow through the brain in during of learning. This work has implicated specific circuits in within the amygdala as essential for the formation of threat memories. The same brain system underlies threat learning in humans. The detailed mechanisms, which can only be uncovered through animal studies are thus applicable to understanding threat processing in the human brain.

Some of the techniques we use to explore threat memory in the brain include pharmacological and viral-based (DREADD and optogenetic) manipulations of brain chemistry, brain lesions, neuroanatomical tract tracing at the light and electron microscopic level, single unit and field recordings of neural activity in awake and anesthetized animals, whole cell recordings in in vitro brain slices, and fMRI in healthy human volunteers and in patients with fear/anxiety disorders.

Ongoing work is exploring th

Joseph LeDoux is the Henry and Lucy Moses Professor of Science at NYU in the Center for Neural Science, and he directs the Emotional Brain Institute of NYU and the Nathan Kline Institute. He also a Professor of Psychiatry and Child and Adolescent Psychiatry at NYU Langone Medical School. His work is focused on the brain mechanisms of memory and emotion and he is the author of The Emotional Brain, Synaptic Self, and Anxious. LeDoux has received a number of awards, including the Karl Spencer Lashley Award from the American Philosophical Society, the Fyssen International Prize in Cognitive Science, Jean Louis Signoret Prize of the IPSEN Foundation, the Santiago Grisolia Prize, the American Psychological Association Distinguished Scientific Contributions Award, the American Psychological Association Donald O. Hebb Award, and Jean-Marie Delwart Foundation 2016 International Prize for Molecular and Cellular Mechanisms Underlying Mood. LeDoux is a Fellow of the American Academy of Arts and Sciences, the New York Academy of Sciences, and the American Association for the Advancement of Sci

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